Table 3.
Alcohol-induced sleep changes in overlap subjects
| N = 6 (four male) | Control sleep Median (IQR) |
Alcohol sleep Median (IQR) |
P value |
|---|---|---|---|
| REM % of TST | 25 (12) | 21 (15) | 0.028 |
| NREM mean ΔPtcCO2, kPa | 0.48 (0.39) | 0.68 (0.27) | 0.028 |
| REM mean ΔPtcCO2, kPa | 0.64 (0.63) | 0.91 (0.35) | 0.028 |
| Sleep mean ΔPtcCO2, kPa | 0.51 (0.46) | 0.75 (0.28) | 0.028 |
| Sleep mean SpO2, % | 93.3 (3.8) | 93.2 (6.5) | 0.075 |
| ODI | 32 (28) | 24 (22) | 0.028 |
| AHI | 39 (40) | 26 (22) | 0.046 |
| REM AHI | 49 (43) | 36 (28) | 0.075 |
| NREM AHI | 31 (46) | 30 (23) | 0.116 |
As no record of daytime sleepiness was available, overlap was defined as having at least 15 apneas/hypopneas per hour of sleep in subjects with chronic obstructive pulmonary disease
NREM mean ΔP tc CO 2 mean pressure of transcutaneous carbon dioxide in non-rapid eye movement sleep, REM mean ΔP tc CO 2 mean pressure of transcutaneous carbon dioxide in rapid eye movement sleep, Sleep mean ΔP tc CO 2 mean pressure of transcutaneous carbon dioxide in REM and NREM sleep, Sleep mean S p O 2 mean oxyhemoglobin saturation during sleep measured by pulse oximetry, REM % of TST REM-sleep percentage of total sleep time, AHI number of apneas/hypopneas per hour of sleep, REM AHI AHI during REM sleep, NREM AHI AHI during NREM sleep