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. 2015 Feb 17;5:8521. doi: 10.1038/srep08521

Figure 2. CCL20 expression in murine APAP-induced liver injury.

Figure 2

(a) Mice received PBS (n = 6) or APAP (6 h, n = 6; 24 h, n = 9; 48 h, n = 11) for indicated time points. Hepatic CCL20 and IL-36γ mRNA was determined by realtime PCR. Target mRNA was normalized to that of GAPDH (means ± SEM versus ctrl of target mRNA, ***p < 0.001 and ##p < 0.01 versus ctrl at the respective time point). (b) Mice received PBS (n = 6) or APAP (24 h (n = 9) or 48 h (n = 6)) or APAP/IL-22 (24 h (n = 9) or 48 h (n = 6)). Hepatic CCL20 mRNA was determined by realtime PCR. Target mRNA was normalized to that of GAPDH (means ± SEM versus ctrl; ***p < 0.001 versus ctrl, ###p < 0.001). (ab) Statistical analysis, one-way analysis of variance with post hoc Bonferroni correction).