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. Author manuscript; available in PMC: 2015 Feb 17.
Published in final edited form as: J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2010 Jul;28(3):188–230. doi: 10.1080/10590501.2010.504980

Figure 3. DNA Strand Breaks by Cr (IV) Reactions* (50).

Figure 3

*Lane 1, untreated control A Hind III-digested DNA in pH 7.4 phosphate buffer; lane 2, same as lane 1 but with 2 mM Cr(IV) added; lane 3, same as lane I but with 0.2%H202 added; lane 4, incubation mixture containing DNA, 2 mM Cr(IV) and 0.2% H20,; lane 5, same as lane 4, but with 5000 waits/m1 catalase added; lane 6, same as lane 4, but with 2 mM deferoxamine added; lane 7, same as lane 4 but with 50 mM sodium formate added; lanes 8-11, same as lane 4, but with 0.1, 1, 2, and 5 mM aspirin added. The samples were incubated for 8 hr.