Table 1. The Rate of Nucleation and Dynamic Instability of MTs Estimated in Our Numerical Modeling.
| Parameter | Mean (1σ-range)a |
|---|---|
| MT growth velocity (μm/s)b | 0.079 (0.058–0.11) |
| MT shrinkage velocity (μm/s) | 0.11 (0.065–0.19) |
| Catastrophe frequency (/s) | 0.041 (0.0097–0.17) |
| Rescue frequency (/s) | 0.071 (0.011–0.47) |
| Cytoplasmic nucleation (×10−4/s μm2)b | 3.2 (2.1–5.0) |
| Branching nucleation (×10−4/s μm2)c | 0.49 (0.074–3.3) |
| Severing (×10−4/s μm2)c | 1.4 (0.57–3.4) |
n = 9.
a
See Methods for the calculation of the mean and 1σ(sd)-range.
b
The maximum value at the onset of simulation when the monomer concentration is the highest.
c
The maximum value at the end of simulation (12 min after the washout) when the total MT length is the largest.