Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison between BBI608 and current cancer therapeutics. FaDu cancer stem cells were treated for 24 h with DMSO (control), BBI608 (2 μM), sunitinib (20 μM), gemcitabine (2 μM), or carboplatin (32 μM). RNA was isolated, reverse transcribed, and then analyzed by quantitative PCR for stem cell genes: β-catenin, Nanog, SMO, and SOX2. GAPDH was used as a housekeeping gene to which the data were normalized.
