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. 2015 Feb 17;9:9. doi: 10.3389/fnana.2015.00009

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Copyright © 2015 Navarro, Alvarado, Navarrete, Giner, Obregon, Manzanares and Berbel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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VGluT1-ir and VGAT-ir bouton distribution in CA3 of C and MMI pups. Histograms showing the VGluT1-ir and VGAT-ir bouton distribution in CA3 of C and MMI pups. The VGluT1-ir and VGAT-ir bouton density and percentage decreased in the MMI stratum lucidum, and bouton density increased in the stratum radiatum (A–D). Despite of the differences found in the VGluT1-ir and VGAT-ir bouton density and percentage in MMI pups, the VGAT-ir bouton percentage in each stratum was similar in all groups (E). The VGluT1-ir bouton area decreased in MMI10 strata pyramidale and lucidum (F). The VGAT-ir bouton area decreased in MMI10 strata pyramidale and lacunosum-moleculare, and in MMI21 stratum lacunosum-moleculare (G). n.s. indicates not significant differences; (^*) and (^**) indicate significant differences, P ≤ 0.05 and P ≤ 0.001, respectively.