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. 2015 Feb 17;9:9. doi: 10.3389/fnana.2015.00009

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Copyright © 2015 Navarro, Alvarado, Navarrete, Giner, Obregon, Manzanares and Berbel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prepulse inhibition of the acoustic startle response and elevated plus maze tests. Bar diagram showing the the startle amplitude (A), percentage of prepulse inhibition (B), and time spent in open arms (C) of C and MMI pups at P40. In MMI pups, both the acoustic startle response amplitude and the percentage of prepulse inhibition at 74, 82 and 90 dB prepulses decreased, while the percentage of time in the open arms of the elevated plus-maze increased and the number of transitions decreased (D). (^*) and (^**) indicate significant differences, P ≤ 0.05 and P ≤ 0.001, respectively.