Table 1.
Patient characteristics and clinical parameters.
| HTx-CTRL (n = 9) | HTx-LVAD (n = 8) | ||
|---|---|---|---|
| Pre-LVAD | Post-LVAD | ||
| Age (years), mean ± SE | 52 ± 3 | 46 ± 4 | — |
| Male gender (n) | 5 | 8 | — |
| Duration of LVAD assistance (days), mean ± SE | — | — | 357 ± 66 |
| Ischemic heart disease (IHD) (n) | 2 | 1 | — |
|
| |||
| Cardiac index (L/min/m2), mean ± SE | 1.90 ± 0.17 | 1.61 ± 0.13 | 2.82 ± 0.30#∗∗ |
| PCWP (mm Hg), mean ± SE | 14 ± 3 | 24 ± 5 | 9 ± 3* |
| PASP (mm Hg), mean ± SE | 33 ± 4 | 47 ± 6 | 27 ± 3* |
| PADP (mm Hg), mean ± SE | 13 ± 2 | 23 ± 3‡ | 12 ± 4* |
| LVEF (%), mean ± SE | 26 ± 2 | 21 ± 2 | 28 ± 3* |
| LVESV (mL), mean ± SE | 147 ± 17 | 282 ± 27‡ | 160 ± 20** |
| LVEDV (mL), mean ± SE | 196 ± 18 | 357 ± 32§ | 219 ± 18** |
| LVEDD (mm), mean ± SE | 66 ± 2 | 80 ± 3§ | 70 ± 3* |
| NT-proBNP (ng/L), mean ± SE | 2976 ± 1562 | 4800 ± 991 | 576 ± 145** |
# P < 0.05 versus HTx-CTRL; ‡ P < 0.01 versus HTx-CTRL; § P < 0.001 versus HTx-CTRL; * P < 0.05 versus pre-LVAD; ** P < 0.01 versus pre-LVAD.
PCWP: pulmonary capillary wedge pressure; PASP: pulmonary artery systolic pressure; PADP: pulmonary artery diastolic pressure; LVEF: left ventricular ejection fraction; LVESV: left ventricular end-systolic volume; LVEDV: left ventricular end-diastolic volume; LVEDD: left ventricular end-diastolic diameter; NT-proBNP: N-terminal prohormone of brain natriuretic peptide.