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. 2015 Feb 1;2015:729831. doi: 10.1155/2015/729831

Figure 5.

Figure 5

TM-1 administered 3 or 4 h after injury reduced the TBI-induced AQP4 protein level measured 8 and 24 h after TBI. The AQP4 protein level showed a marked decrease following TM-1 administration (10 mg/kg) 3 and 4 h after injury, respectively. Rats were sacrificed 8 or 24 h after TBI. Data are expressed as mean ± SD (n = 5/group). ** P < 0.01 and *** P < 0.001 TBI + veh group compared with the sham-operated group; # P < 0.05 TM-1 treated groups compared with the TBI + veh groups; no significance in AQP4 protein expression following TM-1 administration (10 mg/kg) at 3 and 4 h after injury in the rats sacrificed at 8 or 24 h after TBI.