Figure 3.
Metabolic oscillations that are terminated with Dz can be restored in some cases (A) but not others (B). (A) Continuation of simulation in Figure 2B with KCl added at t = 120 min, simulated by raising the K+ reversal potential from −75 mV to −50 mV. Cac rises but remains nonoscillatory, and FBP oscillations are restored. (B) FBP oscillations cannot be restored when JGK is increased slightly (0.19 μM ms−1).