Fig. 6.

Palmitate annuls insulin sensitivity of mitochondrial function. L6 myoblasts were exposed to BSA-conjugated palmitate (PA) or BSA as described in Section 2.2. 2-Deoxyglucose (2DG) uptake (panel A), cell respiratory control (panel B), and coupling efficiency (panel C) were measured following incubation without (white bars) or with 100 nM insulin (black bars). The data shown are means ± SEM of 5 independent experiments. The asterisks indicate statistical significance between insulin-exposed and control cells (P < 0.05).