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. 2015 Feb 17;10(2):e0117399. doi: 10.1371/journal.pone.0117399

Table 2. The receiver-operating characteristic (ROC) curve efficacies and cutoff points of near vision acuity (NVA), distance vision acuity (DVA) and the series combined test.

Disease Method AUC* criterion YI § Se. ¥ Sp. PPV NPV
High hyperopia (N = 38) DVA 0.77 ≤20/32 0.50 89.5 60.6 1.93 99.85
NVA 0.85 ≤20/25 0.60 81.6 78.9 3.24 99.80
Combined 0.86 DVA≤20/32 NVA ≤20/25 0.64 78.9 84.8 4.30 99.78
High myopia (N = 377) DVA 0.95 ≤20/50 0.79 97.1 81.7 33.15 99.67
NVA 0.91 ≤20/25 0.70 85.9 84.3 33.86 98.47
Combined 0.97 DVA≤20/63 NVA ≤20/20 0.79 87.8 90.7 46.95 98.76
High astigmatism (N = 107) DVA 0.77 ≤20/32 0.48 86.9 61.3 5.28 99.47
NVA 0.85 ≤20/25 0.63 83.2 79.9 9.30 99.48
Combined 0.87 DVA≤20/25 NVA ≤20/25 0.64 81.3 83.1 10.65 99.44
All SREs (N = 486) DVA 0.91 ≤20/40 0.70 91.2 76.8 32.69 98.60
NVA 0.91 ≤20/25 0.71 85.2 86.2 43.26 97.92
Combined 0.95 DVA≤20/32 NVA ≤20/25 0.76 83.5 92.6 58.25 97.85

Note: *AUC: area under the curve

§YI: Youden Index

¥Se.: Sensitivity

Sp.: Specificity

PPV: positive predictive value

NPV: negative predictive value

SREs: significant refractive errors