Table 1. Mucosal-to-serosal fluxes of FD4 and HRP for basal and monochloramine-stimulated colonic mucosa of pigs born to control or antibiotic-treated sows and slaughtered at different ages (LSmeans and SEM, n = 6–8 per treatment and age).
| Sow’s treatment | Control | Antibiotics | Statistics (P =) 1 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Offspring’s age | d14 | d28 | d42 | d14 | d28 | d42 | SEM | treat. | age | treat.*age |
| FD4 | ||||||||||
| FD4, basal (ng/cm²/h) | 304 | 213 | 148 | 240 | 235 | 108 | 47 | 0.50 | 0.012 | 0.74 |
| FD4, + monochloramine (% basal) | 155 | 172 | 134 | 131 | 225 | 185 | 40 | 0.45 | 0.51 | 0.51 |
| HRP | ||||||||||
| HRP, basal (ng/cm²/h) | 19 | 19 | 10 | 32 | 9 | 18 | 10 | 0.67 | 0.37 | 0.53 |
| HRP, + monochloramine (% basal) | 191 β | nd 2 | 386 β | 1496 α | nd | 293 β | 444 | 0.103 | 0.18 | 0.066 |
1Treat.: Treatment of sows pre- and post-partum (control versus antibiotic); age (d14 and d28, unweaned; d42 weaned from d28); treat*age: treatment by age interaction.
2nd: not calculated by the analysis of variance (MIXED model) due to low and unbalanced numbers (n = 2–3) of available HRP data at day 28.
α, β LS means with different superscript letters in a row differ (P<0.10).