Table 1. Summary of membrane properties of DG granule cells in different groups.
Parameters | Control (n = 16 of 7 rats) | EC-Aβ (n = 19 of 8 rats) | EC-Aβ+ ISR (n = 15 of 5 rats) | EC-Aβ+ NIM (n = 14 of 4 rats) |
---|---|---|---|---|
RMP (mV) | -73.38 ± 1.653 | -74.43 ± 1.135 | -78.31 ± 2.580 | -73.25 ± 1.887 |
Threshold (mV) | -39.38 ± 1.139 | -39.33 ± 1.162 | -40.01 ± 1.397 | -39.09± 0.81 |
Peak Amplitude (mV) | 69.72 ± 1.816 | 72.87 ± 2.174 | 68.20 ± 2.564 | 66.74 ± 3.13 |
Rise slope 10–90% (mV/ms) | 73.56 ± 6.306 | 76.65 ± 6.002 | 76.15 ± 8.053 | 72.70 ± 6.895 |
Decay slope 10–90% (mV/ms) | -26.00 ± 2.828 | -30.40 ± 2.851 | -29.60 ± 2.941 | -28.91 ± 1.865 |
Half width (ms) | 1.713 ± 0.081 | 1.547 ± 0.07 | 1.716 ± 0.043 | 1.788 ± 0.1 |
Values are mean ± SEM. One way ANOVA showed no significant difference between different groups.