Table 2.
Baseline characteristics of participants included in the power analysis for 24-month and 60-month RCTa
|
|
||||||
|---|---|---|---|---|---|---|
| 2 years analysis | 5 years analysis | |||||
| Carrier (n=56) | Non-Carrier (n=78) | p-valueb | Carrier (n=31) | Non-Carrier (n=57) | p-valueb | |
| Age | 43.93±6.49 | 44.99±10.07 | 0.49 | 41.37±4.36 | 45.35±11.05 | 0.06 |
| Education | 7.84±4.57 | 7.29±3.97 | 0.92 | 6.74±4.93 | 6.86±4.96 | 0.92 |
| Sex (%M/F) | 39/61 | 22/78 | 0.03 | 35/65 | 37/63 | 0.89 |
| MMSE | 26.63±4.01 | 28.95±1.79 | 1.27e-5 | 26.97±2.36 | 28.53±2.10 | 2.01e-3 |
| Verbal Fluency (Animal) | 15.51±5.08 | 18.33±4.45 | 1.01e-3 | 17±4.77 | 18.82±3.91 | 0.06 |
| Boston Naming | 12.02±2.23 | 12.64±2.01 | 0.01 | 12.3±2.14 | 12.44±1.93 | 0.77 |
| CERAD Word List-Immediate | ||||||
| Correct | 13.49±5.90 | 17.78±4.83 | 1.18e-5 | 15.43±4.88 | 17.24±4.81 | 0.11 |
| Intrusions | 3.55±4.54 | 1.45±2.09 | 5.06e-4 | 2.87±2.75 | 1.56±3.27 | 0.07 |
| CERAD Word List-Recall | ||||||
| Correct | 3.75±2.89 | 6.49±2.22 | 1.08e-8 | 4.23±2.74 | 6.47±2.07 | 5.73e-5 |
| Intrusions | 1.34±1.62 | 0.6±1.44 | 7.20e-3 | 1.03±1.50 | 0.56±1.40 | 0.15 |
| CERAD Recognition of words | ||||||
| Correct “yes” | 8.6±1.70 | 9.55±1.03 | 1.19e-4 | 9.13±1.11 | 9.35±1.44 | 0.49 |
| Correct “no” | 8.81±1.82 | 9.9±0.41 | 1.23e-6 | 9.3±1.18 | 9.73±1.10 | 0.01 |
| Constructional Praxis | 9.26±1.57 | 9.51±1.6 | 0.38 | 9.7±1.21 | 9.6±1.62 | 0.77 |
| Trail Making Test-A | ||||||
| Errors | 1.11±3.63 | 0.28±1.39 | 0.08 | 0.37±1.55 | 0.13±0.49 | 0.31 |
| Time | 115.43±80 | 81.39±61.55 | 0.01 | 93.07±50.94 | 86.96±50.95 | 0.62 |
| Recall of drawings | 7.2±7.01 | 14.06±7.15 | 3.08e-7 | 8.18±7.76 | 13.63±7.51 | 2.16e-3 |
| Raven’s Progressive Matrices | 7.92±2.28 | 8.41±2.08 | 0.21 | 8.03±2.06 | 8.36±2.23 | 0.51 |
MMSE, Mini-Mental State examination
a
All data are mean±SD unless otherwise stated.
b
Baseline group differences were compared using two-tailed T-Test, and Chi Square test.