Table 4.

Recent developments in bioconjugation at Cys residues.

Entry	Residue	Reagent(s)	Product	Reference
1	Cys			Standard reagents; see (Chalker et al., 2009a; Hermanson, 2013; Kim et al., 2008)
2	Cys
3	Cys
4	Cys
5	Cys
6	Cys			(Marculescu et al., 2014)
7	Cys			(Bryden et al., 2014)
8	Cys			(Koniev et al., 2014)
9	Cys			(Abbas et al., 2014)
10	Cys, Lys			(Hong et al., 2009a; Kislukhin et al., 2011; Kislukhin et al., 2012)
11	Cys	pH 5.5–8.0		(Toda et al., 2013)
12	Cys	pH 6–8 NaBH4		(Badescu et al., 2014)
13	Cys	AuCl/AgOTf CH3CN/H2O		(On-Yee Chan et al., 2013)
14	Cys			(Crich et al., 2006)
15	Cys			(Spokoyny et al., 2013)
16	Cys			(Hoppmann et al., 2012; Hoppmann et al., 2014)
17	Cys	(50 mM) pH 10–11		(Bernardes et al., 2008)
18	Cys	hν or AIBN		(Dondoni et al., 2009; Li et al., 2012)