Table 1.
Trait | Overall (N=191) |
CAC Present | AAC Present | ||
---|---|---|---|---|---|
No (N=134) | Yes (N=57) | No (N=60) | Yes (N=131) | ||
CAC Agatston Score* | 0 (0–21.5) | 0 (0–0) | 85.5 (26.6–283.2) | 0 (0–0) | 0 (0–52.8) |
AAC Agatston Score* | 92.3 (0–686.0) | 43.9 (0–272.0) | 728.5 (55.1–1794.0) | 0 (0–0) | 302.3 (78.5–1085.8) |
Serum SOST (pmol/L) | 45.2 (15.6) | 43.7 (16.5) | 48.7 (12.8) | 46.5 (17.4) | 44.6 (14.8) |
Age (years) | 62.9 (8.0) | 61.2 (7.3) | 66.9 (8.4) | 58.0 (5.8) | 65.2 (7.9) |
Body Mass Index (kg/m2) | 27.9 (4.2) | 27.6 (4.0) | 28.7 (4.7) | 27.2 (3.9) | 28.3 (4.4) |
Total Body Fat (%) | 23.8 (6.3) | 23.4 (6.2) | 24.9 (6.4) | 22.3 (5.9) | 24.5 (6.4) |
Current smoking (%) | 11.0 | 10.5 | 12.5 | 6.7 | 13.0 |
Ever Smoked (%) | 35.1 | 31.3 | 44.6 | 30.0 | 37.4 |
>3 Drinks per week (%) | 15.7 | 14.9 | 17.9 | 18.3 | 14.5 |
Walking >1hr per week (%) | 53.9 | 54.5 | 53.6 | 60.0 | 51.1 |
Grip Strength (kg) | 39.5 (9.0) | 40.3 (8.3) | 37.6 (10.3) | 41.4 (9.8) | 38.6 (8.5) |
Diabetes (%) | 30.7 | 27.6 | 36.8 | 21.7 | 34.9 |
Diabetes Medication (%) | 23.4 | 20.2 | 29.8 | 15.0 | 27.3 |
Hypertension (%) | 56.0 | 49.3 | 71.4 | 40.0 | 63.4 |
Antihypertensive Medication (%) | 34.0 | 25.4 | 53.6 | 21.7 | 39.7 |
LDL-c (mg/dL) | 131.4 (39.7) | 129.9 (40.8) | 135.3 (37.3) | 128.2 (39.3) | 132.8 (40.0) |
HDL-c (mg/dL) | 44.2 (12.0) | 44.5 (10.7) | 43.5 (15.0) | 46.5 (11.0) | 43.2 (12.4) |
Triglycerides (mg/dL)* | 94.0 (73.0–123.5) | 94.0 (71.0–120.0) | 96.0 (79.0–140.0) | 102.5 (76.5–121.5) | 93.0 (70.5–126.0) |
Statin Use (%) | 11.6 | 9.9 | 14.5 | 3.3 | 15.5 |
eGFR (ml/min/1.73m2) | 84.1 (15.7) | 85.8 (15.5) | 79.9 (15.5) | 86.6 (14.5) | 82.9 (16.2) |
Characteristics shown as Mean(SD) or Frequency, as appropriate. Significant differences by CAC or AAC status are underlined (P<0.05) and/or bolded (P<0.01)
Due to skewed trait median(IQR) shown
CAC: coronary artery calcification; AAC: aortic artery calcification; SOST: sclerostin; LDL-c: low-density lipoprotein cholesterol; HDL-c: high density lipoprotein cholesterol