Figure 5. Lipid-mixing inhibition by 4E10 antibody.
CpreTM-primed vesicles were incubated with increasing amounts of MAb4E10 prior to the addition of target vesicles (circles). Cala-primed vesicles were used as negative control to probe the specificity of the process (squares). The dotted line begins at the paratope-to-peptide ratio of 0.5:1. Plotted values are means±SD of three experiments.