Hematoxylin and eosin stained Hp 2-2 DM plaque showing intraplaque hemorrhage at the site
of brachiocephalic artery bifurcation with the aortic arch. The prevalence of intraplaque
hemorrhage was increased in Hp 2-2 brachiocephalic plaques (8/10 Hp 2-2 plaques vs. 0/11
Hp 1-1 plaques, p<0.001).
A. 10X magnification. Intraplaque clot is indicated by arrow.
B. 40X magnification of boxed inset region from (A)
demonstrating numerous red blood cells (arrows) derived from an intraplaque hemorrhage
within the plaque.