Fig. 1.

Droplet-based microreactor and cell sorter using DEP. Cells expressing and secreting a target antibody (depicted in grey) and cells not expressing a target antibody (depicted in orange) are encapsulated in droplets with a fluorescent detection antibody, incubated off-chip to permit the production of secretion antibodies, and sorted according to the increased fluorescence signal from the localized packing of detection antibodies on the surface of the bead covered with capture and secretion antibodies. Reprinted with permission from Mazutis et al²⁹ Copyright 2013 Nature Publishing Group.