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. 2015 Mar;6(2):40–50. doi: 10.1177/2040622314567678

Table 3.

Approved indications and dosages of lubiprostone.

Indication Dose (by mouth) Gender Pregnancy category
Chronic idiopathic constipation 24 µg twice daily Male and female C
Irritable bowel syndrome with constipation 8 µg twice daily Female C
Opioid-induced constipation 24 µg twice daily Male and Female C