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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Respir Med. 2014 Oct 22;109(2):255–264. doi: 10.1016/j.rmed.2014.10.004

Table 3.

Predicted change in FEV1 and FEV1/FVC per year for a 1 SD increase in log-adhesion molecule

Change per year per SD
log-adhesion molecule
(95% CI)
P-value
sICAM-1
FEV1, mL (n=1,629)
 Model 1 −0.51 (−2.97, 1.95) 0.69
 Model 2 −0.55 (−3.02, 1.93) 0.66
 Model 3 −0.54 (−3.02, 1.93) 0.67
FEV1/FVC, % (n=1,605)
 Model 1 −0.03 (−0.10, 0.03) 0.27
 Model 2 −0.03 (−0.10, 0.02) 0.25
 Model 3 −0.03 (−0.10, 0.02) 0.25

sE-selectin
FEV1, mL (n=899)
 Model 1 0.20 (−3.06, 3.45) 0.91
 Model 2 0.10 (−3.17, 3.37) 0.95
 Model 3 0.11 (−3.17, 3.38) 0.95
FEV1/FVC, % (n=888)
 Model 1 −0.05 (−0.13, 0.03) 0.23
 Model 2 −0.05 (−0.15, 0.03) 0.23
 Model 3 −0.05 (−0.15, 0.03) 0.23

Model 1: adjusted for age, sex, race, educational attainment, height and weight (model for FEV1 also adjusted for height2)

Model 2: additionally adjusted for smoking status and pack-years for ever-smokers

Model 3: additionally adjusted for C-reactive protein