Table 2.
Efficacy of MBSR at Time 2 and Time 3
| Time 2 Outcomes | Adjusted Means | |||||||
|---|---|---|---|---|---|---|---|---|
| Dependent Variables | MBSR (N=18) | Control (N=17) | Diff | SE diff | p* | Pooled SD | Effect Size | 95% CI Effect Size |
| FSI Interference | 2.11 | 4.58 | −2.47 | 0.47 | <0.001 | 1.73 | −1.43 | −1.96, −0.90 |
| FSI Severity | 3.03 | 5.57 | −2.54 | 0.45 | <0.001 | 1.64 | −1.55 | −2.09, −1.01 |
| FSI Fatigue Days (0-7 scale) | 3.36 | 5.56 | −2.20 | 0.53 | <0.001 | 2.03 | −1.08 | −1.60, −0.57 |
| FSI Percent of Day Fatigued | 2.34 | 5.65 | −3.31 | 0.53 | <0.001 | 1.81 | −1.83 | −2.41, −1.25 |
| SF-36 Vitality | 52.96 | 33.22 | 19.75 | 4.54 | <0.001 | 15.35 | 1.29 | 0.71, 1.87 |
| Sheehan Disability Scale | 2.60 | 3.49 | −1.12 | 0.66 | 0.25 | 2.51 | −0.45 | −0.96, 0.07 |
| PHQ-8 Depression | 4.58 | 10.03 | −5.46 | 1.10 | <0.001 | 4.18 | −1.30 | −1.82, −0.79 |
| GAD-7 Anxiety | 3.91 | 5.92 | −2.00 | 1.20 | 0.104 | 4.24 | −0.47 | −1.02, 0.08 |
| ISI Sleep Disturbance | 7.72 | 12.76 | −5.04 | 1.41 | 0.001 | 6.81 | −0.74 | −1.15, −0.33 |
| Time 3 Outcomes | Adjusted Means | |||||||
|---|---|---|---|---|---|---|---|---|
| Dependent Variables | MBSR (N=18) | Control (N=17) | Diff | SE diff | P* | Pooled SD | Effect Size | 95% CI Effect Size |
| FSI Interference | 1.88 | 4.59 | −2.70 | 0.55 | <0.001 | 2.01 | −1.34 | −1.88, −0.81 |
| FSI Severity | 3.22 | 5.54 | −2.32 | 0.44 | <0.001 | 1.51 | −1.54 | −2.10, −0.97 |
| FSI Fatigue Days (0-7 scale) | 3.62 | 6.05 | −2.44 | 0.57 | <0.001 | 2.00 | −1.22 | −1.77, −0.66 |
| FSI Percent of Day Fatigued | 2.48 | 5.79 | −3.31 | 0.63 | <0.001 | 1.92 | −1.73 | −2.37, −1.08 |
| SF-36 Vitality | 56.49 | 30.42 | 26.08 | 4.76 | <0.001 | 15.09 | 1.73 | 1.11, 2.35 |
| Sheehan Disability Scale | 2.09 | 4.69 | −2.60 | 0.62 | <0.002 | 2.13 | −1.22 | −1.79, −0.65 |
| PHQ-8 Depression | 3.59 | 11.91 | −8.32 | 1.26 | <0.001 | 4.86 | −1.71 | −2.22, −1.20 |
| GAD-7 Anxiety | 3.39 | 7.82 | −4.43 | 1.29 | 0.002 | 4.54 | −0.98 | −1.53, −0.42 |
| ISI Sleep Disturbance | 6.57 | 13.36 | −6.78 | 1.74 | <0.001 | 6.76 | −1.00 | −1.51, −0.50 |
Note. Results are based on ANCOVA models comparing MBSR and controls at T2, and separately at T3, adjusting for T1 measure of the outcome variables, baseline mental health treatment, and the observing and describing subscales of the Five Facet Mindfulness Questionnaire. All Fatigue Symptom Inventory (FSI) subscales are rated on 0-10 scales except where indicated. The effect size for the SF-36 Vitality scale is in the opposite direction than the FSI effect sizes because the SF-36 Vitality scale is scored such that a higher score represents better vitality.
*
Using Bonferroni correction for multiple comparisons, only p-values < 0.00278 (=.05/18) are considered significant.