Table 4.

Correlation coefficients between behavioral results and neuron numbers¹.

Genotype	Behavioral test 2,3,4	Neuron number by Brain Region
		Cerebral cortex neurons	CA3 Pyramidal cells	CA1 Pyramidal cells	Dentate Gyrus neurons
Wild type	Open Field	NS	−0.322*	NS	NS
	Morris maze	NS	NS	NS	NS
	PPI	NS	NS	NS	NS
nNOS−/−	Open Field	−0.320*	NS	−0.360*	−0.346*
	Morris maze	0.444**	NS	0.453**	NS
	PPI	0.301*	NS	0.310*	NS
Wild type and nNOS−/− combined	Open Field	−0.370**	−0.394**	−0.350**	−0.418**
	Morris maze	0.370**	0.279**	0.346**	0.293**
	PPI	0.210*	0.266*	0.230*	0.242*

¹Numbers are Pearson Correlation Coefficients.

²For the Open Field Test, the total number of lines crossed was analyzed. Thus, the negative correlation coefficients imply that, as the number of neurons increased, the number of lines crossed decreased.

³For the Morris Water Maze, the percent time spent in the target quadrant during the probe trial was analyzed. The positive correlation coefficients imply that, as the number of neurons increased, the time spent in the target quadrant increased.

⁴For the paired pulse inhibition test (PPI), the percent inhibition at 16 dB was analyzed. Thus, the positive correlation coefficients imply that, as the number of neurons increased, the percent inhibition in response to the prepulse increased.

^*Significant at the 0.05 level.

^**Significant at the 0.01 level.

NS = not significant.