Table 5.
Combination genotypes analysis of XRCC1 codons 194, 399, and −77T>C.
| Combined genotypes | Case N (%) | Control N (%) | χ 2 | OR (95% CI) | P | OR (95% CI)* | P * |
|---|---|---|---|---|---|---|---|
| CC/GG/TT | 39 (11.2) | 43 (10.6) | Reference | 1.00 | — | — | — |
| CT/GA/TT | 68 (19.5) | 71 (17.6) | 0.04 | 1.06 (0.61, 1.82) | 0.85 | 0.95 (0.53, 1.72) | 0.87 |
| CT/GG/TT | 65 (18.7) | 72 (17.8) | 0.00 | 0.99 (0.58, 1.72) | 0.99 | 0.88 (0.49, 1.60) | 0.68 |
| CC/GA/TT | 60 (17.2) | 66 (16.3) | 0.00 | 1.00 (0.57, 1.75) | 0.99 | 1.02 (0.56, 1.87) | 0.95 |
| TT/GG/TT | 29 (8.3) | 37 (9.2) | 0.19 | 0.86 (0.45, 1.66) | 0.66 | 0.91 (0.45, 1.84) | 0.80 |
| CT/GG/CT | 16 (4.6) | 38 (9.4) | 4.35 | 0.46 (0.22, 0.96) | 0.04 | 0.52 (0.24, 1.13) | 0.10 |
| CC/AA/TT | 23 (6.6) | 23 (5.7) | 0.07 | 1.10 (0.53, 2.27) | 0.79 | 0.86 (0.39, 1.92) | 0.72 |
| CC/GA/CT | 17 (4.9) | 23 (5.7) | 0.28 | 0.81 (0.38, 1.75) | 0.60 | 0.74 (0.32, 1.70) | 0.48 |
| CC/GG/CT | 20 (5.7) | 22 (5.4) | 0.00 | 1.00 (0.48, 2.11) | 1.00 | 1.09 (0.50, 2.42) | 0.82 |
| CT/GA/CT | 4 (1.1) | 2 (0.5) | 0.23 | 2.21 (0.38, 12.71) | 0.63 | 1.18 (0.18, 7.74) | 0.86 |
| CC/AA/CT | 1 (0.3) | 3 (0.7) | 0.14 | 0.37 (0.04, 3.68) | 0.71 | 0.37 (0.04, 3.87) | 0.41 |
| CT/AA/TT | 3 (0.9) | 1 (0.2) | 0.31 | 3.31 (0.33, 33.13) | 0.58 | 3.74 (0.36, 38.83) | 0.27 |
| Others | 3 (0.9) | 3 (0.9) | — | — | — | — | — |
| Total | 348 (100) | 404 (100) | — | — | — | — | — |
*adjusted for age, gender, smoking, drinking, and family history of cancer.