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. Author manuscript; available in PMC: 2015 Feb 18.
Published in final edited form as: Bull Math Biol. 1992 Jan;54(1):95–116. doi: 10.1007/BF02458622

Figure 1.

Figure 1

Schematic diagram of the model. The sarcoplasmic reticulum (SR) comprises of: (1) Main Calcium Store (MCS) into which Ca2+ entering by diffusion is bound by the binding substance B; (2) a Releasable Terminal (RT) which releases Ca2+ to the sarcoplasmic space; (3) the longitudinal SR which sequesters Ca2+ from the sarcoplasmic space. Free Ca from MCS (Caf) and LSR (CaLSR) are transferred to RT with time constants τfr and τLSRJin and Jout are the trans-sarcolemmal influx and efflux respectively. JioCa and Jio are Ca–Ca exchange between Cae and CaRT. Cae is the [Ca2+] between sarcolemma and SR; Casp is the sarcoplasmic Ca2+.