Table 2.
Factors associated with active tuberculosis during one year follow-up of ART-naïve patients entering HIV care (n=1900)
| Univariate | Multivariate | |||
|---|---|---|---|---|
|
|
|
|||
| Factorsa | HR (95% CI) | p | HR (95% CI) | p |
| History of injecting drug use | 1.76 (1.33–2.32) | <0.001 | 1.71 (1.25–2.35) | 0.001 |
| CD4 cell count, per 10 cells/µl | 0.94 (0.93–0.96) | <0.001 | 0.97 (0.95–0.98) | <0.001 |
| Age | 1.03 (1.01–1.04) | 0.007 | 1.02 (0.99–1.04) | 0.199 |
| Haemoglobin, g/dl | 0.78 (0.74–0.81) | <0.001 | 0.83 (0.78–0.88) | <0.001 |
| Oral thrush | 3.43 (2.64–4.46) | <0.001 | 1.66 (1.19–2.29) | 0.002 |
| Antiretroviral treatmentb | 1.22 (0.95–1.57) | 0.122 | 0.91 (0.68–1.23) | 0.555 |
a
Factors are determined at enrolment in HIV care
b
antiretroviral treatment was taken into account as time-dependent variable. Data were missing for CD4 cell count (n=108), age (n=28), haemoglobin (n=205), oral thrush (n=105) and ART (n=2). For multivariate analyses, all individuals with missing data were excluded (n=213). ART, antiretroviral treatment; HR, hazard ratio; CI, confidence interval.