Table 1.

Extract of the key recommendations and suggestions of the Surviving Sepsis Campaign guidelines [3]

●	Early quantitative resuscitation of the septic patient during the first 6 hours after recognition (1C)
●	Blood cultures before antibiotic therapy (1C)
●	Imaging studies performed promptly to confirm a potential source of infection (UG)
●	Administration of broad-spectrum antimicrobials therapy within 1 hour of the recognition of septic shock (1B) and severe sepsis without septic shock (1C) as the goal of therapy
●	Reassessment of antimicrobial therapy daily for de-escalation, when appropriate (1B)
●	Infection source control with attention to the balance of risks and benefits of the chosen method within 12 hours of diagnosis (1C)

Principles of the Grading of the Recommendations Assessment, Development, and Evaluation (GRADE) system to guide assessment of quality of evidence from high (A) to very low (D) and to determine the strength of recommendations as strong (1) or weak (2). UG, ungraded.