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. 2015 Feb 17;10(2):e0117361. doi: 10.1371/journal.pone.0117361

Table 1. Resistance to first- and second-line antituberculosis drugs.

New cases (N = 1174) Re-treated cases (N = 597)
n (%) 95% CI n (%) 95% CI
Susceptibility to all four first-line drugs 796 (67.7) 65.1–70.4 280 (47.0) 43.0–51.0
Any resistance to first-line drugs 378 (32.3) 29.6–34.9 317 (53.0) 49.0–57.0
 Isoniazid (INH) 202 (17.3) 15.1–19.4 218 (36.4) 32.5–40.3
 Rifampin (RMP) 125 (10.6) 8.9–12.4 172 (28.9) 25.2–32.5
 Ethambutol (EMB) 52 (4.4) 3.2–5.6 70 (11.9) 9.2–14.3
 Streptomycin (SM) 310 (26.4) 23.9–28.9 233 (39.1) 35.2–43.0
Resistance to INH or RMP 126 (11.7) 9.8–13.7 113 (24.6) 20.7–28.6
Multidrug resistance (MDR) 101 (8.6) 7.0–10.2 138 (23.2) 19.8–26.5
Susceptibility to ofloxacin (OFX) and kanamycin (KM) 1084 (92.3) 90.7–93.8 505 (84.7) 81.8–87.6
Any resistance to OFX or KM 91 (7.7) 6.2–9.3 91 (15.3) 12.4–18.2
 OFX resistance 66 (5.6) 4.3–6.9 68 (11.4) 2.7–4.8
 KM resistance 44 (3.7) 2.7–4.8 43 (7.2) 5.1–9.3
MDR + resistance to OFX or KM 64 (5.6) 4.2–6.9 74 (12.8) 10.0–15.5
Extensive drug resistance ¥ 14 (1.2) 0.6–1.8 15 (2.5) 1.3–3.8

First-line antituberculosis drugs include isoniazid, rifampin, ethambutol, and streptomycin; second-line antituberculosis drugs include ofloxacin and kanamycin.

Multidrug resistance was defined as resistance to at least isoniazid and rifampin.

¥ Extensive drug resistance was defined as resistance to at least isoniazid, rifampin, ofloxacin, and kanamycin.