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. 2015 Feb 17;10(2):e0117478. doi: 10.1371/journal.pone.0117478

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© 2015 Kayashima et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — (A) LOD curves for the arch lesion with sex as an additive covariate (black line) and as an interactive covariate (red line). X-axis represents chromosome number and y-axis represents the LOD score. The horizontal dashed lines represent the thresholds for significant QTL (P = 0.05) and suggestive QTL (P = 0.63) in the sex-interactive model. (B) LOD curves for arch lesion in males (blue line) and females (red line). The horizontal dashed lines represent the thresholds for significant QTL (P = 0.05) in males (blue) and females (red). (C and D) LOD curves for the arch lesion on Chr 2 (C) and Chr 10 (D) with sex as an interactive covariate (black), in males (blue) and in females (red). X-axis represents positions on chromosome (cM) and y-axis represents the LOD score.