Table 1. Plasmatic parameters in young, aged, and C29-treated aged F344 rats.
| YR | AR | ARC | ARR | |
|---|---|---|---|---|
| GSH (μM) | 6.6±2.4 | 5.0±0.7 | 6.2±1.6 | 6.5±2.2 |
| ROS (μM) | 4679.8±111.2 | 6164.5±2259.1 # | 5471.8±1990.7 | 5991.4±1517.3 |
| SOD (U/mL) | 2.6±0.1 | 2.3±0.2 # | 2.5±0.5 | 2.7±0.4 |
| MDA (nmol/mL) | 26.6±6.4 | 58.4±11.2 # | 46.3±17.9 | 37.5±17.5 |
| CRP (pg/mL) | 304.4±171.0 | 755.5±150.6 # | 352.6±97.4* | 446.4±96.6* |
| TNF-α (pg/mL) | 28.6±13.6 | 100.1±12.7 # | 46.1±30.1* | 46.0±34.9# |
| IL-1β (pg/mL) | 12.3±6.1 | 169.0±61.0 # | 62.3±22.8* | 63.6±29.4* |
| IL-4 (pg/mL) | 50.7±12.4 | 34.4±9.6 # | 35.9±9.2 | 35.7±6.4 |
| IL-6 (pg/mL) | 7.8 ±7.3 | 21.7±11.6 # | 13.6±10.4 | 14.4±10.3 |
| IL-10 (pg/mL) | 45.5±14.3 | 28.1±19.9 # | 37.3±16.3* | 39.1±15.7 |
YR, young rats; AR, aged rats; ARC, aged rats treated with C29, ARR, aged rats treated with rapamycin
# p< 0.05 compared with YR;
*, p< 0.05 compared with AR.