Table 1. Clinical presentations of SCA3/MJD patients.
Clinical features | Genotypes | ||
---|---|---|---|
G/G | G/A | A/A | |
Age at onset Mean ± SD (range) a |
|||
37.70 ± 9.90 (17–59) | 36.19 ± 9.84 (14–57) | 34.09 ± 9.45 (15–53) | |
Duration Mean ± SD (range) |
|||
10.16 ± 3.87 (5–25) | 11.77 ± 5.14 (5–25) | 11.95 ± 4.30 (7–20) | |
Ataxia symptoms, No (%) | 55 (100%) | 83 (100%) | 32 (100%) |
Pyramidal sign | 15 (8.82%) | 22 (12.94%) | 14 (8.23%) |
Extrapyramidal signs | 10 (5.88%) | 17 (10.00%) | 5 (2.94%) |
a. Before adjusting for the mean size of expanded CAG repeats in the patients