Fig. 3.

Mean percent change from baseline in BMD response at the a lumbar spine, b total hip, c femoral neck, and d greater trochanter over 2 years (Japanese phase 2 study [94]). Reprinted from Itabashi A et al. (2011) Effects of bazedoxifene on bone mineral density, bone turnover, and safety in postmenopausal Japanese women with osteoporosis. J Bone Miner Res 26: 519–529, with permission from John Wiley and Sons. c2011 American Society for Bone and Mineral Research. BMD bone mineral density, BZA bazedoxifene. ^a p ≤ 0.001 vs placebo; ^b p < 0.01 vs placebo; ^c p < 0.05 vs placebo