Table 3.
Pharmacokinetic parameters of five subjects
AUC0–τ a (μg h/ml) | C max a (μg/ml) | t max b (h) | |
---|---|---|---|
Lapatinib | 48.2 (34.6, 67.1) | 3.52 (2.57, 4.82) | 5.55 (3.02, 5.93) |
Capecitabine | 4.00 (3.01, 5.31) | 2.70 (1.49, 4.88) | 1.90 (0.53, 3.25) |
5-FU | 0.51 (0.35, 0.76) | 0.28 (0.13, 0.63) | 1.90 (0.53, 3.25) |
FBAL | 29.0 (26.4, 32.0) | 5.77 (5.00, 6.66) | 3.05 (2.00, 4.25) |
aGeometric mean (95 % confidence interval)
bMedian (range)