Fig. 1.
IP3R3-tauGFP targeting construct used to generate the IP3R3tm1(tauGFP) mouse. The targeting construct includes flanking DNA with 3′ and 5′ regions complementary to the sequence in the Itpr3 gene as well as a cassette encoding for tauGFP (amplified from the IRES-tauGFP-LNL plasmid).