Table 3.
Functional analysis of 204 down-regulated target genes of UPmiRs and 295 up-regulated target genes of DNmiRs in IPA "Diseases and Functions".
| Diseases and Functions | UPmiRs | DNmiRs | ||
|---|---|---|---|---|
| p value | Count | p value | Count | |
| Lipid Metabolism | 3.85E-06 | 22 | ||
| Cellular Growth and Proliferation | 9.18E-06 | 26 | 5.17E-10 | 77 |
| Connective Tissue Disorders | 1.12E-04 | 11 | ||
| Energy Production | 5.59E-04 | 5 | ||
| Metabolic Disease | 8.11E-04 | 8 | ||
| RNA Post-Transcriptional Modification | 1.10E-03 | 3 | ||
| Nervous System Development and Function | 1.57E-03 | 25 | 5.27E-28 | 61 |
| Tissue Development | 1.60E-03 | 34 | 6.33E-29 | 96 |
| Cell-To-Cell Signaling and Interaction | 1.64E-03 | 12 | 6.33E-29 | 54 |
| Cell Death and Survival | 4.27E-03 | 12 | 4.85E-24 | 105 |
| Cellular Assembly and Organization | 4.68E-03 | 17 | 6.33E-29 | 65 |
| Cellular Movement | 6.92E-03 | 6 | 4.52E-09 | 58 |
| Cell Cycle | 1.06E-02 | 4 | 2.28E-07 | 32 |
| Organismal Survival | 1.82E-11 | 99 | ||
| Total number of UPmiR-targets: 57 | ||||
| Total number of DNmiR-targets: 168 | ||||