Table 1.

Prediction accuracy of HLA-VBSeq and existing tools for HLA typing in the 30x simulation data analysis.

HLA resolution	HLA-VBSeq	PHLAT	HLAminer
8-digit	99.94%	-	-
6-digit	99.95%	80.80%	-
4-digit	99.95%	88.75%	50.12%
2-digit	100%	96.39%	77.82%

The accuracies of each method are calculated at 8-digit, 6-digit, 4-digit, and 2-digit resolution from the 30x simulation data. PHLAT only predicts HLA types at 6-digit, 4-digit and 2-digit resolution, and HLAminer only predicts HLA types at 4-digit and 2-digit resolution.