Table 2.
LP/Lean, short physical performance battery (SPPB), and 400-m backward elimination (BE) regression models at baseline
| β ± SE | P-value | |
|---|---|---|
| LP/Lean: Adjusted R2 = 0.22, P = 0.0009 | ||
| Sex | 4.2 ± 1.4 | 0.003 |
| FA Factor 9: 2-hydroxypalmitate, 2-hydroxystearate | 1.6 ± 0.6 | 0.01 |
| AA Factor 6: Hydrocinnamate, cinnamoylglycine | −1.4 ± 0.6 | 0.03 |
| Age | −0.4 ± 0.2 | 0.05 |
| Dipeptide Factor 3: γ-glutamylamino acids | −1.3 ± 0.6 | 0.05 |
| AA Factor 19: N-acetylglycine | 1.2 ± 0.6 | 0.07 |
| SPPB: Adjusted R2 = 0.15, P = 0.001 | ||
| AA Factor 6: Hydrocinnamate, cinnamoylglycine | −0.4 ± 0.2 | 0.008 |
| AA Factor 7: N-methylproline, N,N-dimethylproline | −0.4 ± 0.2 | 0.009 |
| 400-m: Adjusted R2 = 0.41, P < 0.0001 | ||
| Age | −0.0 ± 0.0 | 0.0005 |
| AA Factor 19: N-acetylglycine | 0.1 ± 0.0 | 0.0006 |
| AC Factor 4: Isobutyrylcarnitine | −0.1 ± 0.0 | 0.004 |
| AA Factor 4: BCAA degradation products, indolelactate | 0.0 ± 0.0 | 0.005 |
| AA Factor 12: Phenol Sulfate | −0.1 ± 0.0 | 0.009 |
| Sex | 0.1 ± 0.0 | 0.01 |
| AA Factor 5: BCAA | −0.0 ± 0.0 | 0.02 |
| AA Factor 13: Trans-urocanate | −0.0 ± 0.0 | 0.08 |
BCAA, branched-chain amino acids; LP/Lean, leg press one repetition maximum divided by total lean mass.
Sex, age, total fat (LP/Lean model) or BMI (SPPB, 400-m models), and principal components analysis factors that were associated (P ≤ 0.10 and q ≤ 0.30) with measures of physical function were considered as candidate variables for BE linear regression. Covariates significantly associated (P ≤ 0.10) with LP/Lean, SPPB, and 400-m are shown with parameter estimates and standard errors (β ± SE), in order of significance (P-value).