Table 1.
The top 20 biological processes assigned to the development-regulating HOTAIR by LncRNA2Function.
| GO term | Background frequency | Sample frequency | P-value | Corrected P-value |
|---|---|---|---|---|
| System development | 3253/20447 | 38/74 | 1.63E-12 | 2.37E-08 |
| Anatomical structure morphogenesis | 1884/20447 | 28/74 | 2.45E-11 | 7.10E-08 |
| Tissue development | 1183/20447 | 23/74 | 1.33E-11 | 7.10E-08 |
| Embryonic skeletal system development | 120/20447 | 10/74 | 1.73E-11 | 7.10E-08 |
| Anatomical structure development | 3717/20447 | 39/74 | 2.07E-11 | 7.10E-08 |
| Skeletal system development | 388/20447 | 14/74 | 1.01E-10 | 2.44E-07 |
| Organ morphogenesis | 790/20447 | 18/74 | 2.89E-10 | 4.73E-07 |
| Multicellular organismal development | 3830/20447 | 38/74 | 2.56E-10 | 4.73E-07 |
| Developmental process | 4248/20447 | 40/74 | 2.93E-10 | 4.73E-07 |
| Organ development | 2271/20447 | 29/74 | 3.63E-10 | 5.27E-07 |
| Skeletal system morphogenesis | 189/20447 | 10/74 | 1.54E-09 | 1.72E-06 |
| Multicellular organismal process | 5336/20447 | 44/74 | 1.39E-09 | 1.72E-06 |
| Single-multicellular organism process | 5125/20447 | 43/74 | 1.51E-09 | 1.72E-06 |
| Extracellular matrix organization | 204/20447 | 10/74 | 3.23E-09 | 3.28E-06 |
| Extracellular structure organization | 205/20447 | 10/74 | 3.39E-09 | 3.28E-06 |
| Head development | 52/20447 | 6/74 | 3.26E-08 | 2.96E-05 |
| Embryonic skeletal system morphogenesis | 91/20447 | 7/74 | 3.86E-08 | 3.30E-05 |
| Single-organism developmental process | 3161/20447 | 31/74 | 4.39E-08 | 3.54E-05 |
| Chordate embryonic development | 557/20447 | 13/74 | 9.05E-08 | 6.57E-05 |
| Embryo development ending in birth or egg hatching | 564/20447 | 13/74 | 1.05E-07 | 7.23E-05 |