Table 1.
Patient characteristics and response assessment
| Sex | Age (yrs) | Genetic status | TTP (mo) | Survival (mo) | Metabolic response (modified EORTC) | Anatomic response (RECIST 1.0) |
|---|---|---|---|---|---|---|
| Female |
79 |
Exon 11 insertion PYD577-582 |
4.7 |
12.9 |
PMR |
PR |
| Female |
61 |
Exon 17 D820Y |
10.2 |
19. 3 |
SMD |
PR |
| Female |
69 |
Amplified |
7.4 |
8.8 |
SMD |
PD |
| Male |
57 |
Amplified |
5.0 |
11.5 |
PMD |
PD |
| Female |
62 |
Amplified |
2.6 |
11.9 |
SMD |
PD |
| Male |
69 |
Amplified |
5.8 |
16.2 |
PMR |
PD |
| Female |
81 |
Amplified |
1.0 |
3.8 |
PMD |
PD |
| Female |
72 |
Amplified |
1.3 |
9.8 |
PMD |
PD |
| Female |
55 |
Amplified |
10.6 |
18.3 |
SMD |
SD |
| Female |
59 |
Amplified |
0.9 |
2.8 |
PMD |
PD |
| Female |
59 |
Exon 11 L576P |
27.1 |
27.1 |
PMR |
PR |
| Female |
75 |
Amplified |
5.6 |
12.5 |
PMD |
SD |
| Female |
47 |
Exon 11 L576P |
2.6 |
7.3 |
PMR |
PR |
| Male |
84 |
Amplified |
1.6 |
21.8 |
PMD |
PD |
| Female |
53 |
Exon 11 deletion WKVVE557-560 |
10.6 |
24.3 |
SMD |
SD |
| Male |
66 |
Exon 13 K642E |
0.9 |
1.5 |
PMD |
PD |
| Female | 66 | Exon 11 L576P | 3.4 | 5.5 | PMR | PR |
PMR = Partial Metabolic Response, SMD = Stable Metabolic Disease, PMD = Progressive Metabolic Disease, PR = Partial Response, SD = Stable Disease, PD = Progressive Disease, TTP = Time to Progression.