Table. 1. Hematological parameters for the SD rats during the 4-week recovery period study.
Group/ Dose (mg/kg) | Sex | Mean S.D. N | RBC (× 106 cells/μL) | HGB (g/dL) | HCT (%) | RBC Indices | PLT (× 103 cells/μL) | Reti(%) | WBC (X 103 cells/μL) | WBC Differential Counting (%) | PLT (sec) | APTT (sec) | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MCV | MCH | MCHC | NEU | LYM | MONO | EOS | BASO | |||||||||||
G1 0 |
Male | Mean | 8.91 | 14.8 | 45.5 | 51.1 | 16.6 | 32.4 | 1134 | 2.3 | 10.68 | 14.7 | 79.2 | 2.6 | 0.9 | 0.2 | 14.5 | 16.8 |
S.D. | 0.33 | 0.7 | 1.6 | 1.8 | 0.7 | 0.8 | 32 | 0.5 | 2.76 | 5.9 | 6.2 | 0.8 | 0.3 | 0.1 | 0.6 | 1.9 | ||
N | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | ||
Female | Mean | 7.83 | 14.3 | 42.7 | 54.5 | 18.3 | 33.6 | 1074 | 2.1 | 5.89 | 14 | 80.3 | 2.7 | 0.9 | 0.1 | 14.4 | 17 | |
S.D. | 0.16 | 0.6 | 1.2 | 1 | 0.6 | 0.6 | 83 | 0.3 | 1.91 | 1.7 | 1.8 | 0.5 | 0.3 | 0.1 | 0.5 | 1.4 | ||
N | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | ||
G4 0.28 |
Male | Mean | 8.88 | 15.1 | 45.7 | 51.4 | 17 | 33.1 | 1090 | 2.1 | 8.79 | 15.1 | 80.5 | 2.2 | 0.9 | 0.2 | 14.5 | 16.8 |
S.D. | 0.42 | 0.7 | 2.4 | 1.2 | 0.6 | 0.7 | 178 | 0.2 | 2.1 | 7.4 | 7.5 | 0.7 | 0.2 | 0 | 0.7 | 2.4 | ||
N | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | ||
Female | Mean | 8.15 | 14.4 | 43.1 | 52.8 | 17.7 | 33.4 | 953 | 1.8 | 7.02 | 11.8 | 82.9 | 2.5 | 1.1 | 0.2 | 14.4 | 18 | |
S.D. | 0.12 | 0.5 | 1.4 | 1.4 | 0.4 | 0.2 | 98 | 0.3 | 1.83 | 4.2 | 4.9 | 0.6 | 0.2 | 0.1 | 0.3 | 0.8 | ||
N | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
Significant difference from control by Student t-test: *P <0.05, **P < 0.01; RBC, red blood cell; HGB, hemoglobin; HCT, hematocrit; MCV, mean corpuscular cell volume; MCHC, mean corpuscular cell hemoglobin concentration; WBC, white blood cell; PLT, platelet; PT, prothrombin time; APTT, active partial thromboplastin time; NEU, neutrophils; LYM, lymphocytes; MONO, monocytes; EOS, Eosinophils; BASO, basophils; Reti, reticulocytes.