Table 4.
Lesion-based analysis: performance comparisons between PET/CT and cePET/CT
| PET/CT | cePET/CT | |
|---|---|---|
| Sensitivity (%) |
80.54 (76.41–84.10) |
91.38 (88.25–93.74) |
| Specificity (%) |
54.45 (47.37–61.36) |
50.26 (43.24–57.28) |
| Positive predictive value (%) |
78.99 (74.80–82.63) |
79.61 (75.72–83.02) |
| Negative predictive value (%) |
56.83 (49.59–63.79) |
73.28 (65.12–80.12) |
| Positive likelihood ratio |
1.77 (1.50–2.09) |
1.84 (1.58–2.13) |
| Negative likelihood ratio |
0.36 (0.28–0.45) |
0.17 (0.12–0.24) |
| Diagnostic odds ratio |
4.93 (3.39–7.21) |
10.63 (6.85–16.84) |
| Error rate (%) |
27.81 (24.36–31.53) |
21.78 (18.65–25.26) |
| Accuracy (%) |
72.19 (68.47–75.64) |
78.22 (74.74–81.35) |
| Youden’s index | 0.349 (0.352–0.347) | 0.416 (0.418–0.414) |
Estimated parameters corresponding to each technique are presented with a 95% confidence interval shown within parentheses. PET, positron emission tomography; CT, computed tomography; cePET/CT, contrast-enhanced PET/ CT.