Table 5.
Statistical difference ( P values) between the performance of PET/CT and cePET/CT for each analyzed tumor type, site of disease, and clinical question
| P value | |
|---|---|
| Tumor type |  | 
| Lung cancer | 0.12 | 
| Head and neck cancer | 0.02 | 
| Gastrointestinal cancera | 0.0002 | 
| Breast cancer | 0.09 | 
| Lymphoma | 0.24 | 
| Melanoma | 0.16 | 
| Multiple melanoma | 0.08 | 
| Otherb | 0.33 | 
| Site of disease |  | 
| Neck | 0.096 | 
| Thorax | 0.36 | 
| Abdomen | 0.009 | 
| Skeleton-bone marrow | 0.33 | 
| Lymph nodes | 0.44 | 
| Clinical question |  | 
| Diagnosis | 0.39 | 
| Staging | 0.09 | 
| Restagingc | 0.003 | 
| Response to chemotherapy | 0.13 | 
| Response to radiotherapy | 0.1 | 
| Post-surgery evaluation | 0.54 | 
| Surveillance | 0.51 | 
aIncluding esophageal, gastric, and colorectal cancer.
bGynecologic malignancy n = 8 , testicular cancer n = 2, sarcoma n = 3, low-differentiated neuroendocrine carcinoma n = 4, thymoma n = 1.
cSuspected relapse or patients with potentially resectable metastatic disease.
PET, positron emission tomography; CT, computed tomography; cePET/CT, contrast-enhanced PET/ CT.