Figure 1.

Example images of mutants with high or low levels of phenotypic variation

Cell walls are labeled with FITC-conjugated concanavalin A (magenta) and nuclei are labeled with DAPI (green). DAmP-YDR355C (phenotypic potential = 3.25), DAmP-RNA1 (phenotypic potential = 1.81), DAmP-NOP1 (phenotypic potential = 3.07), DAmP-IWS1 (phenotypic potential = 2.14), DAmP-CDC42 (phenotypic potential = 2.54), and DAmP-ERG12 (phenotypic potential = 1.61) are all high-confidence phenotypic stabilizers. R1158 (phenotypic potential = −0.05) does not contain any essential gene mutations. DAmP-MEX67 (phenotypic potential = −1.42) and DAmP-FBA1 (phenotypic potential = −1.01) are DAmP strains that display low phenotypic variation.