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. 2014 Dec 18;2(12):e12240. doi: 10.14814/phy2.12240

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© 2014 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Renin release from juxtaglomerular (JG) cells under basal conditions (Control), after incubation with ET‐1 (10 nmol/L), or ET‐1 plus different concentrations of the ETA receptor blocker BQ123 (0, 5 μmol/L, 1 μmol/L and 5 μmol/L). Incubation with ET‐1 reduced renin release. This response was inhibited by 5 μmol/L of an ETA receptor blocker. *P <0.05 versus control.