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. 2014 Dec 18;2(12):e12240. doi: 10.14814/phy2.12240

Figure 8.

Figure 8.

Renin release from juxtaglomerular (JG) cells under basal conditions (Control) or after incubation with ET‐1 (10 nmol/L) at the top, and ET‐2 (10 nmol/L) at the bottom. The IP3 inhibitor 2‐APB (100 μmol/L) alone did not change basal renin release. ET‐1 and ET‐2 significantly decreased renin release, and incubation with both 2‐APB and either ET‐1 or ET‐2 returned renin release at values similar to control. *P <0.05 versus control.