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. 2015 Feb 9;9:265–274. doi: 10.2147/PPA.S61651

Table 2.

Teriflunomide: factors potentially influencing patient preference in MS

Efficacy Comparable to interferon beta-1a sc tiw in the TENERE study6
Route of administration Oral
Dosing frequency Once daily
Half-life 19 days (median)
Pharmacovigilance Initially frequent liver enzyme controls (every 2 weeks)
Side effects (selection only) Arterial hypertension
Gastrointestinal disorders (diarrhea, nausea)
Hair thinning
Hematological abnormalities (leucopenia, lymphopenia)
Liver enzyme increase

Abbreviations: MS, multiple sclerosis; sc, subcutaneous; TENERE, TErifluNomidE and REbif.®; tiw, three times weekly.