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. 2015 Feb 18;6:30. doi: 10.3389/fneur.2015.00030

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Copyright © 2015 Sandow, Kim, Raue, Päsler, Klaft, Antonio, Hollnagel, Kovacs, Kann, Horn, Vajkoczy, Holtkamp, Meencke, Cavalheiro, Pragst, Gabriel, Lehmann and Heinemann.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Typical experiments in sister-slices from the same hippocampal specimen show persistence of SLE at the end of each protocol sequences (control, AED, AED + MDTIs, washout). (A) In the dentate gyrus (DG), (B) in the subiculum (SUB), S1 slice 1 with application of CBZ, S2 slice 2 with application of VPA for both regions. The drugs applied are described above the pairs of traces, which display [K⁺]_o (top), and field potential (FP) bottom. Amplitudes and time are given by calibration bars on the right.