. 2015 Feb 13;10:39. doi: 10.1186/s13014-015-0341-8

Table 3.

Genotypes, minor allele frequency, Hardy-Weinberg Equilibrium and single-marker association analysis in all selected SNPs

Genes	SNPs	Alleles ^a (1/2)	Genotypes (11/12/22)	MAF	HWE	Corrected P values ^b			1-β	SS _0.8
Genes	SNPs	Alleles ^a (1/2)	Genotypes (11/12/22)	MAF	HWE	Additive	Dominant	Recessive	1-β	SS _0.8
SOD2	rs4880	G/A	4/24/100	0.1250	0.1065	0.9588	0.9588	0.9588	0.0230	1371
SOD3	rs2536512	A/G	10/60/58	0.3125	0.4103	0.9588	0.9609	0.9588	0.0030	7785
CAT	rs769217	T/C	29/69/30	0.4961	0.4792	0.9588	0.9657	0.9588	0.0040	5862
PON1	rs662	T/C	15/49/64	0.3086	0.2986	0.0842	0.0528	0.9588	0.5240	194
	rs705379	T/C	35/49/44	0.4648	0.0124	0.0842	0.0842	0.4988	0.3020	283
PPARG	rs3856806	T/C	8/43/77	0.2305	0.6168	0.9588	0.9588	0.9588	0.0130	2072
ADIPOQ	rs1501299	T/G	8/56/64	0.2812	0.5107	0.9657	0.9588	0.9588	0.0030	8510
	rs2241766	G/T	9/59/60	0.3008	0.3994	0.9657	0.9657	0.9588	0.0050	5443
IL10	rs1800872	G/T	17/47/64	0.3164	0.1012	0.8279	0.9588	0.5357	0.0660	684
TGFB1	rs1800469	G/A	20/61/47	0.3945	1	0.9588	0.9588	0.9588	0.0100	2632
	rs1800470	A/G	21/61/46	0.4023	1	0.9588	0.9588	0.9588	0.0220	1404
	rs4803455	A/C	20/50/58	0.3516	0.1203	0.9588	0.9588	0.9588	0.0080	3085
NOS3	rs1799983	T/G	1/29/98	0.1211	0.6926	0.9657	0.9813	0.9588	0.0040	5862

^aAllele 1 is the minor allele and allele 2 is the major allele.

^bCorrected P values after false discovery rate correction for multiple testing (including the 39 tests in the single-marker association analyses between the 13 SNPs and carotid plaque score across the three genetic models).

Post-RT duration and number of cardiovascular risk factors were adjusted using linear regression in all association analyses. Statistical power (1-β) was calculated using the model with smallest observed P value. SS_0.8 was the sample size to achieve a statistical power of 0.8 in the corresponding analysis. MAF, minor allele frequency; HWE, Hardy-Weinberg Equilibrium.