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. 2015 Feb 5;14:56. doi: 10.1186/s12936-015-0567-9

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© Daou et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Relation between antibodies at the beginning and clinical protection during the transmission season. Humoral responses at the beginning of the transmission season were assessed by ELISA against (A) AMA-1, (B) MSP-1₁₉, (C) MSP-3, (D) CSP and (E) GLURP-R0. The n = 91 children who developed parasitaemia by PCR or thick smear during follow-up were divided into two groups: a group consisting of asymptomatic children who experienced no clinical episode of malaria during the transmission season (n = 47), and a group of children who had a symptomatic malaria episode at least once during the transmission season (n = 44). Differences between the two groups were analysed by linear regression of log-transformed (log10) data, adjusting values for age. Age adjusted P values are shown for each plot, with p-values without age adjustment (Mann–Whitney U test) in brackets. Scatter plots show individual data points, horizontal lines indicate the median of the group and error bars the interquartile range (IQR).